A company identified the relationship between a certain gene and increased breast cancer risk. They patented that association. Bioethicist Art Caplan asks, why not patent the moon and the stars? Medscape Business of Medicine (Source: Medscape Today Headlines)
MedWorm Sponsor Message: Have a look at The Breast Cancer Daily, the new breast cancer portal with all the latest breast cancer news and research powered by MedWorm, updated daily.
Date: 18 Jun 2013
According to the American Cancer Society, nearly 40,000 women in the United States will succumb to breast cancer this year. Most of these women will die not from the primary tumor but rather tumor recurrence - the reappearance of the disease following treatment. Precisely what causes breast cancer recurrence has been poorly understood. But now a piece of the puzzle has fallen into place: Researchers at the Perelman School of Medicine, University of Pennsylvania have identified a key molecular player in recurrent breast cancer - a finding that suggests potential new therapeutic strategies... (Source: Health News from Medical News Today)
Date: 18 Jun 2013
A protein used by embryo cells during early development, and recently found in many different types of cancer, apparently serves as a switch regulating the spread of cancer, known as metastasis, report researchers at the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Center in the journal Cancer Research. Metastasis is responsible for 90 percent of cancer-related deaths. More than 575,000 Americans die of cancer each year, the second leading cause of death in the United States after cardiovascular disease... (Source: Health News from Medical News Today)
Date: 18 Jun 2013
A drug approved in Europe to treat osteoporosis has now been shown to stop the growth of breast cancer cells, even in cancers that have become resistant to current targeted therapies, according to a Duke Cancer Institute study. The findings, presented at the annual Endocrine Society meeting in San Francisco, indicate that the drug bazedoxifene packs a powerful one-two punch that not only prevents estrogen from fueling breast cancer cell growth, but also flags the estrogen receptor for destruction... (Source: Health News from Medical News Today)
Date: 18 Jun 2013
(Ivanhoe Newswire) – A new study from the Duke Cancer Institute found the drug bazedoxifene, which is currently used in Europe to treat osteoporosis, stops the growth of estrogen-dependent breast cancer cells. Furthermore, the drug even works on breast cancer cells that are resistant to anti-estrogen tamoxifen and aromatase inhibitors, the commonly used targeted therapies for breast cancer. (Source: Medical Headlines From Ivanhoe.com)
Date: 18 Jun 2013
Supporting friends in times of serious trouble, like during an illness, can be difficult. (Source: NYT Health)
MedWorm Sponsor Message: Have a look at The Breast Cancer Daily, the new breast cancer portal with all the latest breast cancer news and research powered by MedWorm, updated daily.
Date: 17 Jun 2013
Supporting friends in times of serious trouble, like during an illness, can be difficult. (Source: NYT Health)
Date: 17 Jun 2013
The Susan G. Komen foundation named a new chief executive to replace Nancy Brinker, founder of the charity, which lost donations after withdrawing funding for Planned Parenthood to screen for breast cancer. Reuters Health Information (Source: Medscape Today Headlines)
Date: 17 Jun 2013
A new molecular pathway involving the gene ZNF365 has been identified and abnormalities in that pathway may predict worse outcomes for patients with breast cancer, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research. "Genomic instability is an increased tendency for abnormal changes in DNA, like the addition of extra copies of chromosomes, DNA breaks and mutations," said Ji-Hye Paik, Ph.D., assistant professor in the Department of Pathology and Laboratory Medicine at Weill Cornell Medical College in New York, N.Y... (Source: Health News from Medical News Today)
Date: 17 Jun 2013
A copper depletion strategy for breast cancer patients with an extraordinarily high-risk of relapse from occult residual disease yields interesting findings about the microenvironment for angiogenesis. Annals of Oncology (Source: Medscape Today Headlines)
Date: 17 Jun 2013
Researchers at Case Western Reserve University have found that a single gene poses a double threat to disease: Not only does it inhibit the growth and spread of breast tumors, but it also makes hearts healthier. In 2012, medical school researchers discovered the suppressive effects of the gene HEXIM1 on breast cancer in mouse models. Now they have demonstrated that it also enhances the number and density of blood vessels in the heart - a sure sign of cardiac fitness... (Source: Health News from Medical News Today)
MedWorm Sponsor Message: Have a look at The Breast Cancer Daily, the new breast cancer portal with all the latest breast cancer news and research powered by MedWorm, updated daily.
Date: 17 Jun 2013
Subgroup analyses from a phase III clinical trial comparing a newer chemotherapy agent called eribulin mesylate, with capecitabine, a standard chemotherapy medication in women with previously treated metastatic breast cancer, showed increased benefit among women sharing certain traits. Specifically, these analyses demonstrated a greater potential benefit in certain subsets of patients with metastatic breast cancer. This analysis was presented by Peter A. Kaufman, M.D., during the 2013 ASCO Annual Meeting... (Source: Health News from Medical News Today)
Date: 17 Jun 2013
Newly discovered genetic variations may help predict breast cancer risk in women who receive preventive breast cancer therapy with the selective estrogen receptor modulator drugs tamoxifen and raloxifene, a Mayo Clinic-led study has found. The study is published in the journal Cancer Discovery. "Our findings are important because we identified genetic factors that could eventually be used to select women who should be offered the drugs for prevention," said James Ingle, M.D., an oncologist at Mayo Clinic. Dr... (Source: Health News from Medical News Today)
Date: 17 Jun 2013
Bazedoxifene, an osteoporosis medication which is approved in Europe, stops the growth of breast cancer cells, including those that are resistant to current medications, researchers from the Duke Cancer Institute reported at ENDO 2013 - The Endocrine Society's Annual Meeting in San Francisco, California, June 15th, 2013. The team explained that bazedoxifene not only blocks estrogen so that it cannot fuel breast cancer cell growth, but it also makes sure the estrogen receptor is killed off - it flags the estrogen receptor for destruction... (Source: Health News from Medical News Today)
Date: 17 Jun 2013
(American Association for Cancer Research) A new molecular pathway involving the gene ZNF365 has been identified and abnormalities in that pathway may predict worse outcomes for patients with breast cancer, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research. (Source: EurekAlert! - Medicine and Health)
Date: 16 Jun 2013
(Springer) Have you ever thought that you knew something about the world in the blink of an eye? It turns out that radiologists can do this with mammograms, the x-ray images used for breast cancer screening. Cytologists, who screen micrographic images of cervical cells to detect cervical cancer, have a similar ability. A new study, published in Springer's journal Psychonomic Bulletin & Review, takes a closer look at the skill these specialists have. (Source: EurekAlert! - Social and Behavioral Science)
MedWorm Sponsor Message: Have a look at The Breast Cancer Daily, the new breast cancer portal with all the latest breast cancer news and research powered by MedWorm, updated daily.
Date: 16 Jun 2013
We know from research that being pregnant while young somehow reduces one’s risk of breast cancer later in life, but why and how? (Source: Breast Cancer Chronicles)
Date: 16 Jun 2013
South Asian women in Britain have an 8% higher risk of developing breast cancer than British white women, compared to a 45% lower risk ten years ago, researchers from the University of Sheffield reported at the National Cancer Intelligence Network Conference in Brighton on Friday, June 14th. Study leader, Dr. Matthew Day and team are not sure why breast cancer incidence has increased so rapidly among British South Asian females... (Source: Health News from Medical News Today)
Date: 16 Jun 2013
(Duke University Medical Center) A drug approved in Europe to treat osteoporosis has now been shown to stop the growth of breast cancer cells, even in cancers that have become resistant to current targeted therapies, according to a Duke Cancer Institute study. (Source: EurekAlert! - Medicine and Health)
Date: 14 Jun 2013
New research suggests it depends on certain gene variations (Source: Cancercompass News: Breast Cancer)
Date: 14 Jun 2013
The scientist who identified one of the genes that causes breast cancer has been awarded a knighthood in the Queen's Birthday Honours. (Source: BBC News | Health | UK Edition)
MedWorm Sponsor Message: Have a look at The Breast Cancer Daily, the new breast cancer portal with all the latest breast cancer news and research powered by MedWorm, updated daily.
Date: 14 Jun 2013
The U.S. Supreme Court ruled this week that the mere act of isolating a DNA sequence does not make human genes patentable. Mary-Claire King, who helped discover the breast cancer gene at the center of the court dispute, discusses the ruling and its implications for genetics.» E-Mail This » Add to Del.icio.us (Source: NPR Health and Science)
Date: 14 Jun 2013
Please find attached a press release by Chugai (Source: Roche Investor Update)
Date: 14 Jun 2013
The Supreme Court announced a unanimous 9-0 decision that genes cannot be patented. After a long legal battle, the high court ruled against Myriad’s patents on two breast cancer susceptibility genes—BRCA1 and BRCA2—declaring that genes are products of nature and cannot be treated as inventions. (Source: Cancer Network)
Date: 14 Jun 2013
Added via Naturejobs. A SFI funded PhD position is available within the Dept of Surgery, Royal College of Surgeons in Ireland. The Endocrine Oncology Research Group (EORG) within the Dept of Surgery focus on the molecular mechanisms underlying endocrine resistance in breast cancer. This project will investigate whether the steroid coactivator protein SRC-1 mediates reprogramming in individual cells to induce survival adaptability and drug resistance in human breast cancer.
The successful candidate will be a highly motivated student with an upper second or first class honours degree in Biochemistry, Genetics or related subject. The research is multidisciplinary using a combination of standard molecular biology techniques, in vivo mouse models and clinical samples.
The d...
Date: 14 Jun 2013
The Supreme Court has unanimously decided that human genes cannot be patented. The ruling was a defeat for the company that controls a genetic breast cancer test used by Angelina Jolie. CBS News contributor Dr. David Agus discusses the ruling and what it means for breast cancer testing. (Source: Health News: CBSNews.com)
MedWorm Sponsor Message: Have a look at The Breast Cancer Daily, the new breast cancer portal with all the latest breast cancer news and research powered by MedWorm, updated daily.
Date: 14 Jun 2013
A new study, published in the journal Cancer Discovery, revealed that genetic variations could be a key indicator of which women are likely and which are unlikely to benefit from tamoxifen or raloxifene for breast cancer prevention. James Ingle, M.D., an oncologist at the Mayo Clinic, who was part of the study, said that the findings are important "because we identified genetic factors that could eventually be used to select women who should be offered the drugs for prevention... (Source: Health News from Medical News Today)
Date: 14 Jun 2013
Title: Which Women Might Benefit From Drugs to Prevent Breast Cancer?Category: Health NewsCreated: 6/13/2013 12:35:00 PMLast Editorial Review: 6/14/2013 12:00:00 AM (Source: MedicineNet Cancer General)
Date: 14 Jun 2013
Radiologists reading breast screening studies had comparable performance regardless (more) (Source: AuntMinnie.com Headlines)
Date: 14 Jun 2013
Nipple delay is a surgical procedure that is part of nipple-sparing mastectomy. It takes place before a mastectomy and reduces the odds of nipple necrosis after breast reconstruction. Nipple delay isn't for everybody, but may benefit some patients. Learn the risks, benefits, and methods for nipple delay procedure. (Source: About.com Breast Cancer)
Date: 13 Jun 2013
Soy is great food - but not everyone agrees on whether or not it's good for your health. Soy foods contain the isoflavone genistein, which may help prevent breast cancer, if you start eating it just before puberty. However, if you've had estrogen-sensitive breast cancer, soy may interfere with your tamoxifen or Aromasin. Learn more about soy and breast cancer. (Source: About.com Breast Cancer)
MedWorm Sponsor Message: Have a look at The Breast Cancer Daily, the new breast cancer portal with all the latest breast cancer news and research powered by MedWorm, updated daily.
Date: 13 Jun 2013
lymph nodes are small bean-shaped parts of the lymphatic system (Source: About.com Breast Cancer)
Date: 13 Jun 2013
Huber needles are used for IV chemotherapy. Your chemo nurse will use a Huber needle to access your implanted port. A Huber needle is designed for patient safety and comfort. Learn about Huber needles here. (Source: About.com Breast Cancer)
Date: 13 Jun 2013
Oncotype DX is a diagnostic test that helps you and your oncologist determine which treatment plan will most effectively prevent your cancer from returning (recurrence) or help to control your disease. If you get a low score on this test, you may be able to avoid chemotherapy. Learn more about Oncotype DX. (Source: About.com Breast Cancer)
Date: 13 Jun 2013
The last part of your clinical breast exam is a manual examination of your nipples and areolas. This is to check for any nipple or areola changes. Although simple to do, your nipple and areola exam is an important part of your clinical breast exam. (Source: About.com Breast Cancer)
Date: 13 Jun 2013
If you are considering breast reconstruction after a mastectomy, and prefer implants to tissue flap surgery (TRAM, DIEP, latissimus dorsi) you will need to know what kinds of implants are available. There are two kinds of implants that are approved for reconstruction. Learn more about saline and silicone breast implants. (Source: About.com Breast Cancer)
MedWorm Sponsor Message: Have a look at The Breast Cancer Daily, the new breast cancer portal with all the latest breast cancer news and research powered by MedWorm, updated daily.
Date: 13 Jun 2013
A breast ultrasound exam is usually done after a mammogram or clinical exam reveals an area of concern that doesn’t show up distinctly. Very little pressure is used, and the exam is usually painless. Since ultrasound uses high-frequency sound waves instead of x-rays, your breast is not exposed to radiation. Here's what to expect during your breast ultrasound exam. (Source: About.com Breast Cancer)
Date: 13 Jun 2013
Atypical lobular hyperplasia is not breast cancer. If you have been diagnosed with atypical lobular hyperplasia, then you need to know how it affects your risk for breast cancer, and how to get a clear diagnosis and treatment options. Learn more about atypical lobular hyperplasia here. (Source: About.com Breast Cancer)
Date: 13 Jun 2013
Mucositis, and particularly oral mucositis, is a common side effect of chemotherapy. MuGard is a prescription mouthwash that has been shown to help with mucositis prevention when used before chemotherapy and radiation treatments. Learn more about MuGard and how it is used for oral mucositis prevention and treatment. (Source: About.com Breast Cancer)
Date: 13 Jun 2013
When breast cancer spreads through the blood or lymph systems to other parts of the body, it has metastasized. (Source: About.com Breast Cancer)
Date: 13 Jun 2013
After breast surgery, you may need to do some arm exercises to regain strength and flexibility. Before you get started, talk to your doctor about doing arm exercises after breast surgery. Here are several easy arm exercises you can do, to keep or regain your range of motion. (Source: About.com Breast Cancer)
MedWorm Sponsor Message: Have a look at The Breast Cancer Daily, the new breast cancer portal with all the latest breast cancer news and research powered by MedWorm, updated daily.
Date: 13 Jun 2013
Here is a list of antidepressants that inhibit the benefits of tamoxifen in women with breast cancer. (Source: About.com Breast Cancer)
Date: 13 Jun 2013
Invasive Lobular Carcinoma (ILC) is a type of breast cancer that starts in the lobules of your breast, where milk is produced. Invasive Lobular Carcinoma does not always feel like a breast lump, because it may grow in a web-like mass. Learn about the symptoms, diagnosis and treatment for Invasive Lobular Carcinoma. (Source: About.com Breast Cancer)
Date: 13 Jun 2013
A fibroadenoma is a benign (non-cancerous) breast tumor that is made of glandular and fibrous breast tissue. Fibroadenomas are very common in premenopausal women, and they can occur in groups. (Source: About.com Breast Cancer)
Date: 13 Jun 2013
Tubular carcinoma is a rare type of invasive ductal carcinoma of the breast. Tubular carcinomas tend to be small, estrogen-receptor positive, HER2/neu negative. Your chance of recovery and survival after treatment for a tubular carcinoma is very good. (Source: About.com Breast Cancer)
Date: 13 Jun 2013
Surgical breast biopsy takes the largest tissue sample and has the highest accuracy rate of all breast biopsy methods. It will leave an external and internal scar but will give you a clear diagnosis of whether your diagnosis is benign or malignant. Learn more about open surgical breast biopsy. (Source: About.com Breast Cancer)
MedWorm Sponsor Message: Have a look at The Breast Cancer Daily, the new breast cancer portal with all the latest breast cancer news and research powered by MedWorm, updated daily.
Date: 13 Jun 2013
Hot flashes and night sweats go with low estrogen levels. Treatments for breast cancer often cause dramatic drops in estrogen, and hot flashes may be severe enough to interfere with your sleep. A Chillow is a small waterbed for your head and shoulders, helping you get to sleep with little or no hot flashes. (Source: About.com Breast Cancer)
Date: 13 Jun 2013
Moderate amounts of coffee and tea do not increase your risk for developing breast cancer. Caffeine in coffee and tea will cause fibrocystic breast lumps to swell, but that will not lead to breast cancer, either. Learn more about coffee and breast cancer. (Source: About.com Breast Cancer)
Date: 13 Jun 2013
Tamoxifen is an estrogen suppressor, which helps lower the risk that breast cancer will return and improves survival rates. If you have been diagnosed with estrogen-receptor positive breast cancer, tamoxifen may be used as part of your follow-up treatment. Weighing the risks and benefits of taking tamoxifen may seem tricky, but most doctors agree that the benefits are much greater than the risks. (Source: About.com Breast Cancer)
Date: 13 Jun 2013
A cyst is a balloon-like sac filled with fluid, gas, or semisolid substances. These can show up anywhere in your body, and can vary in size. (Source: About.com Breast Cancer)
Date: 13 Jun 2013
The breast cancer risk for British Asian women has increased, a study carried out in Leicester has suggested. (Source: BBC News | Health | UK Edition)
MedWorm Sponsor Message: Have a look at The Breast Cancer Daily, the new breast cancer portal with all the latest breast cancer news and research powered by MedWorm, updated daily.
Date: 13 Jun 2013
The Supreme Court’s decision in effect ends a nearly two-decade monopoly by Myriad Genetics on genes that correlate with increased risk of some cancers. (Source: NYT Health)
Date: 13 Jun 2013
Court Also Highlights Patent Eligibility of Method Claims
SALT LAKE CITY, June 13, 2013 -- (Healthcare Sales & Marketing Network) -- Myriad Genetics, Inc. (Nasdaq:MYGN) today said the Supreme Court of the United States upheld its patent claims on comple... Diagnostics, Oncology, LitigationMyriad Genetics, BRCA1, BRCA2, BRACAnalysis, breast cancer (Source: HSMN NewsFeed)
Date: 13 Jun 2013
Gaithersburg, Md., June 13, 2013 -- (Healthcare Sales & Marketing Network) -- GeneDx, one of the world's foremost genetic testing laboratories and a subsidiary of Bio-Reference Laboratories, Inc. (BRLI) announced today its intention to launch a suite of c... Diagnostics, Oncology, Product LaunchBio-Reference Laboratories, GeneDx, BRCA1, BRCA2 (Source: HSMN NewsFeed)
Date: 13 Jun 2013
Source: National Institute of General Medical Sciences -
Related MedlinePlus Page: Breast Cancer (Source: MedlinePlus Health News)
Date: 13 Jun 2013
(Source: NIGMS - What's New)
MedWorm Sponsor Message: Have a look at The Breast Cancer Daily, the new breast cancer portal with all the latest breast cancer news and research powered by MedWorm, updated daily.
Date: 13 Jun 2013
(MedPage Today) -- Two genes may predict which women would benefit from breast cancer primary prevention with tamoxifen or raloxifene (Evista), analysis of the pivotal trials showed. (Source: MedPage Today Hematology/Oncology)
Date: 13 Jun 2013
New research suggests it depends on certain gene variations (Source: The Doctors Lounge - Oncology)
Date: 13 Jun 2013
Newly discovered genetic variations may help predict breast cancer risk in women who receive preventive breast cancer therapy with the selective estrogen receptor modulator drugs tamoxifen and raloxifene, a Mayo Clinic-led study has found. (Source: Mayo Clinic Rochester News)
Date: 13 Jun 2013
Newly discovered genetic markers could be used to select which women would benefit most from chemoprevention with tamoxifen and raloxifene. Medscape Medical News (Source: Medscape Today Headlines)
MedWorm Sponsor Message: Have a look at The Breast Cancer Daily, the new breast cancer portal with all the latest breast cancer news and research powered by MedWorm, updated daily.
Date: 13 Jun 2013
Genetic variations, known as single nucleotide polymorphisms (SNPs), in or near the genes ZNF423 and CTSO were associated with breast cancer risk among women who underwent prevention therapy with tamoxifen and raloxifene, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research. Women who have the favorable variations of these two SNPs are more likely to respond to prevention therapy, according to this study... (Source: Health News from Medical News Today)
Date: 13 Jun 2013
The FDA has approved more than 30 molecularly targeted agents in cancer in recent years, including prominent examples such as trastuzumab for breast cancer, sunitinib for renal cell cancer and bevacizumab for colorectal, non-small cell lung and renal cell cancers.06/13/2013 (Source: Kidney Cancer Association)
Date: 13 Jun 2013
Breast Cancer Campaign invites applications to its pilot grants, to test new hypotheses and generate preliminary data to support a full project grant application.
Grants of up to £20,000 are available for up to one year.
The deadline for applications is 2 September 2013. For more information on the grants please visit the Breast Cancer Campaign website. (Source: Society for Endocrinology)
Date: 13 Jun 2013
An Indiana University cancer researcher and his Canadian collaborator have discovered how normal breast precursor cells may be genetically vulnerable to developing into cancer. David Gilley, Ph.D., associate professor of medical and molecular genetics at the IU School of Medicine and a researcher at the Indiana University Melvin and Bren Simon Cancer Center, and Connie Eaves, Ph.D... (Source: Health News from Medical News Today)
Date: 13 Jun 2013
Telephone-based counseling, when combined with physician advice, can help breast cancer survivors become more physically active, which can improve quality of life and lessen the side effects of cancer treatment, according to new research from The Miriam Hospital. Researchers say women who received exercise advice from their surgeon or oncologist, followed by three months of telephone support, reported 30 more minutes of physical activity per week than patients who received exercise advice and follow-up calls about their general health... (Source: Health News from Medical News Today)
MedWorm Sponsor Message: Have a look at The Breast Cancer Daily, the new breast cancer portal with all the latest breast cancer news and research powered by MedWorm, updated daily.
Date: 13 Jun 2013
For patients with advanced breast cancer, positron emission tomography (PET) and magnetic resonance (MR) imaging can improve quality of life and survival by providing physicians with information on the effectiveness of chemotherapy prior to surgery, said researchers presenting at the 2013 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging. Researchers combined separate imaging systems - PET, MR and CT - to map the course of chemotherapy before surgery, otherwise known as neoadjuvant chemotherapy... (Source: Health News from Medical News Today)
Date: 13 Jun 2013
Two Gene Variants May Predict Who Will Benefit From Breast Cancer Prevention Drugs (Source: eMedicineHealth.com)
Date: 13 Jun 2013
In a unanimous ruling, the United States Supreme Court ruled today that human genes cannot be patented. The ruling invalidates the thousands of patents that have already been granted on human genes, including the patent by Myriad Genetics on the BRCA breast cancer genes... (Source: NaturalNews.com)
Date: 13 Jun 2013
(Case Western Reserve University) Researchers at Case Western Reserve University have found that a single gene poses a double threat to disease: Not only does it inhibit the growth and spread of breast tumors, but it also makes hearts healthier.In 2012, medical school researchers discovered the suppressive effects of the gene HEXIM1 on breast cancer in mouse models. Now they have demonstrated that it also enhances the number and density of blood vessels in the heart. (Source: EurekAlert! - Medicine and Health)
Date: 12 Jun 2013
(NIH/National Institute of General Medical Sciences) In women at high risk for breast cancer, a long-term drug treatment can cut disease risk in half. Researchers have now identified two gene variants that may predict which women are most likely to benefit -- and which should avoid this therapy. There is nearly a six-fold difference in disease risk depending on which gene variants a woman carries. The work represents a major step toward truly individualized breast cancer prevention in high-risk women. (Source: EurekAlert! - Medicine and Health)
MedWorm Sponsor Message: Have a look at The Breast Cancer Daily, the new breast cancer portal with all the latest breast cancer news and research powered by MedWorm, updated daily.
Date: 12 Jun 2013
(University of Pennsylvania School of Medicine) Precisely what causes breast cancer recurrence has been poorly understood. But now a piece of the puzzle has fallen into place: Researchers at the Perelman School of Medicine, University of Pennsylvania have identified a key molecular player in recurrent breast cancer -- a finding that suggests potential new therapeutic strategies. (Source: EurekAlert! - Cancer)
Date: 12 Jun 2013
(Mayo Clinic) Newly discovered genetic variations may help predict breast cancer risk in women who receive preventive breast cancer therapy with the selective estrogen receptor modulator drugs tamoxifen and raloxifene, a Mayo Clinic-led study has found. The study is published in the journal Cancer Discovery. (Source: EurekAlert! - Cancer)
Date: 12 Jun 2013
(American Association for Cancer Research) Genetic variations, known as single nucleotide polymorphisms, in or near the genes ZNF423 and CTSO were associated with breast cancer risk among women who underwent prevention therapy with tamoxifen and raloxifene, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research. (Source: EurekAlert! - Cancer)
Date: 12 Jun 2013
(Source: About.com Alcoholism)
Date: 12 Jun 2013
(MedPage Today) -- Breast cancer deaths varied little between mammography-screened and unscreened populations of women, according to a study of breast cancer mortality trends in England. (Source: MedPage Today Hematology/Oncology)
MedWorm Sponsor Message: Have a look at The Breast Cancer Daily, the new breast cancer portal with all the latest breast cancer news and research powered by MedWorm, updated daily.
Date: 12 Jun 2013
Epidemiological studies have associated both type 2 diabetes and hyperinsulinaemia with breast cancer in women. The Her2 oncogene is associated with metastasis and poor outcome. Ferguson and colleagues used a mouse model of Her2-mediated breast cancer to demonstrate that hyperinsulinaemia results in larger, more aggressive primary tumours, with more numerous lung metastases.
Read the full article in Ferguson et al (2013) Endocrine-Related Cancer 20 391—401, DOI: 10.1530/ERC-12-0333. (Source: Society for Endocrinology)
Date: 12 Jun 2013
Title: Mammography Doesn't Reduce Breast Cancer Death Rates: U.K. StudyCategory: Health NewsCreated: 6/11/2013 6:36:00 PMLast Editorial Review: 6/12/2013 12:00:00 AM (Source: MedicineNet Cancer General)
Date: 12 Jun 2013
(Dartmouth-Hitchcock Medical Center) Subgroup analyses from a phase III clinical trial comparing a newer chemotherapy agent called eribulin mesylate, with capecitabine, a standard chemotherapy medication in women with previously treated metastatic breast cancer, showed increased benefit among women sharing certain traits. Specifically, these analyses demonstrated a greater potential benefit in certain subsets of patients with metastatic breast cancer. This analysis was presented by Peter A. Kaufman, M.D., during the 2013 ASCO Annual Meeting. (Source: EurekAlert! - Medicine and Health)
Date: 11 Jun 2013
UK study claims “no evidence” that screening reduces breast cancer deaths (Source: The Irish Times - Health)
Date: 11 Jun 2013
This is largely because the most common form of cancer in women – breast cancer – is easier to treat than the most common form in men, prostate cancer. The research was carried out by Macmillian Cancer Support. (Source: the Mail online | Health)
MedWorm Sponsor Message: Have a look at The Breast Cancer Daily, the new breast cancer portal with all the latest breast cancer news and research powered by MedWorm, updated daily.
Date: 11 Jun 2013
Nipple Delay Mastectomy Incisions
Art © Pam Stephan
Back in May, Angelina Jolie revealed that she had undergone a double mastectomy with immediate reconstruction. She based that decision on her inherited ...Read Full Post (Source: About.com Breast Cancer)
Date: 11 Jun 2013
But U.S. expert cites flaws in study, notes other research came to different conclusions (Source: The Doctors Lounge - Oncology)
Date: 11 Jun 2013
But U.S. expert cites flaws in study, notes other research came to different conclusions
Source: HealthDay
Related MedlinePlus Pages: Breast Cancer, Mammography (Source: MedlinePlus Health News)
Date: 11 Jun 2013
A new study suggests that breast cancer screening may not have reduced deaths. Decisions about treatment aren't always clear-cut, argues Theodore Dalrymple (Source: Telegraph Health)
Date: 11 Jun 2013
Mandy Brazil, 47, from Worcestershire, booked an appointment with her GP after realising she had some of the warning signs highlighted on TV show, Lorraine. (Source: the Mail online | Health)
MedWorm Sponsor Message: Have a look at The Breast Cancer Daily, the new breast cancer portal with all the latest breast cancer news and research powered by MedWorm, updated daily.
Date: 11 Jun 2013
A new UK study suggests screening for breast cancer does not reduce deaths from the disease. The study, which looked at nearly 40 years of breast screening, adds to the controversy surrounding whether it is screening or improvement in treatment that accounts for the fall in rates of death from breast cancer. The researchers from the Department of Public Health at the University of Oxford, report their findings online in the June issue of the Journal of the Royal Society of Medicine... (Source: Health News from Medical News Today)
Date: 11 Jun 2013
Conclusion
This study of rates of death caused by breast cancer over a 39-year period has found no evidence of the benefits of breast cancer screening. Age-specific mortality rates for women aged between 40 and 49, 50 and 64, and 64 and 74 years peaked prior to the introduction of breast cancer screening in 1988. Declines in mortality were greatest in women under the age of 40 and smallest among women aged 75 years or older.
The researchers found that there were significant changes in downward trend in women aged between 50 and 64 years old – the age group screening is targeted at – but that these occurred in 1979 in Oxford and in 1990 in England. Both of the changes occurred before the introduction of screening, or too soon after the introduction of screening for it to be likely t...
Date: 11 Jun 2013
Breast cancer screening programmes have yet to show a reduction in the number of women who die from the disease, researchers said. (Source: Nursing Times Breaking News)
Date: 11 Jun 2013
Dignitana, a world leader in medical scalp-cooling technology, has announced that it has received U.S. Food and Drug Administration (FDA) approval for its Investigational Device Exemption (IDE) application and is now free to initiate a highly anticipated multi-center, pivotal trial of the patented DigniCap® System. The trial is the second and final phase of study in the United States and paves the way for FDA market approval of the scalp-cooling device, which is already widely used overseas... (Source: Health News from Medical News Today)
Date: 11 Jun 2013
There is ‘no evidence’ that mammograms have helped a greater fall in death rates from breast cancer, according to research into 40 years of British data. (Source: the Mail online | Health)
MedWorm Sponsor Message: Have a look at The Breast Cancer Daily, the new breast cancer portal with all the latest breast cancer news and research powered by MedWorm, updated daily.
Date: 11 Jun 2013
(SAGE Publications) New research analysing breast cancer mortality data spanning almost 40 years concludes that breast cancer screening does not yet show an effect on mortality statistics. The research, published in the Journal of the Royal Society of Medicine, analyzed mortality trends before and after the introduction of the National Health Service Breast Screening Programme in 1988. (Source: EurekAlert! - Medicine and Health)
Date: 10 Jun 2013
(Lifespan) Miriam Hospital researchers say telephone-based counseling, when combined with physician advice, can help breast cancer survivors become more physically active, improving quality of life and lessening the side effects of cancer treatment. (Source: EurekAlert! - Social and Behavioral Science)
Date: 10 Jun 2013
X-ray Structure of the BRCA1 BRCT mutant M1775K
A.N., Ladias, J.A., Foulkes, W.D.
In a landmark ruling, the U.S. Supreme Court handed down its ruling on the patenting of isolated human genes, such as BRCA1...Read Full Post (Source: About.com Breast Cancer)
Date: 10 Jun 2013
25 years of breast cancer screening has failed to significantly reduce deaths from the disease, according to a new study. (Source: Telegraph Health)
Date: 10 Jun 2013
She is leading a major clinical trial in breast cancer and is accused of slipping a poison into the coffee of her lover, a lung cancer specialist. Medscape Medical News (Source: Medscape Today Headlines)
MedWorm Sponsor Message: Have a look at The Breast Cancer Daily, the new breast cancer portal with all the latest breast cancer news and research powered by MedWorm, updated daily.
Date: 10 Jun 2013
Drs. Kathy Miller and Larry Norton talk about breast cancer presentations at ASCO, from data on axillary radiation, aTTom, and adjuvant chemotherapy to BOLERO-3. Medscape Oncology (Source: Medscape Today Headlines)
Date: 10 Jun 2013
The David A. Karnofsky Memorial Award, ASCO’s highest scientific honor, went this year to Dr. Martine J. Piccart, who is internationally recognized for her unflagging dedication and innovative approaches to the development of drugs and regimens that will truly make a difference in the lives of patients with breast cancer. (Source: Cancer Network)
Date: 10 Jun 2013
Most of us are familiar with mammograms - but what are breast MRIs used for, and how do they affect breast cancer treatment decisions? Learn more about breast MRI and how they are used in breast cancer diagnosis and screening. (Source: About.com Breast Cancer)
Date: 09 Jun 2013
Robin Gray is a registered nurse who was misdiagnosed for seventeen months - she was told by several doctors that her breast lump was a cyst. Meanwhile, the lump grew and became painful. Robin tells her story of surviving breast cancer, and how she dealt with her misdiagnosis. (Source: About.com Breast Cancer)
Date: 09 Jun 2013
Cruciferous vegetables - broccoli, cauliflower, radishes, and several types of greens - are full of compounds that help prevent and fight cancer all through your body. Learn how these vegetables boost your health and why they are anticancer foods. (Source: About.com Breast Cancer)
MedWorm Sponsor Message: Have a look at The Breast Cancer Daily, the new breast cancer portal with all the latest breast cancer news and research powered by MedWorm, updated daily.
Date: 09 Jun 2013
Sandi Johnson went in for a mammogram and came out with a diagnosis of Inflammatory Breast Cancer. She was swept up in the whirlwind of treatments: chemotherapy, surgery, radiation. She owns a gym and is fit. Being diagnosed with breast cancer was a shock. Sandi and her network of support made it through the crisis, and she is now holding steady. Here is Sandi Johnson's breast cancer survivor story. (Source: About.com Breast Cancer)
Date: 09 Jun 2013
Breasts have been a symbol of femininity and sexuality since civilization began, so it is not unusual for a breast cancer patient to feel that the disease has attacked her body image along with her breast tissue. Whether a cancer patient preserved her breasts, removed them or reconstructed them, learning to accept and even love a postdiagnosis body is a process. Be sure to include family, friends and especially partners in this aspect of cancer treatment, and never be afraid to talk about your body image issues with a physician. (Source: About.com Breast Cancer)
Date: 09 Jun 2013
Xeloda or capecitabine is an oral chemotherapy drug that you take twice a day with water and on a full stomach. It is used to treat metastatic breast cancer, and can be taken alone or with Taxotere. Read more to learn about how Xeloda works, its side effects, and self-care tips. (Source: About.com Breast Cancer)
Date: 09 Jun 2013
What is a compression sleeve? and how does it relate to arm lymphedema? Learn more about compression sleeves and arm lymphedema here. (Source: About.com Breast Cancer)
Date: 09 Jun 2013
What's Your Risk of breast cancer? Factors that you cannot control, and factors that increase your risk, but are under your control (Source: About.com Breast Cancer)
MedWorm Sponsor Message: Have a look at The Breast Cancer Daily, the new breast cancer portal with all the latest breast cancer news and research powered by MedWorm, updated daily.
Date: 09 Jun 2013
Radiation and chemotherapy can lower your blood counts. A complete blood count (CBC) is a routine blood test done regularly during treatment for breast cancer. A CBC will reveal such conditions as anemia, low levels of red blood cells, or thrombocytopenia, or low levels of platelets. (Source: About.com Breast Cancer)
Date: 09 Jun 2013
Your annual screening mammogram comes with some discomfort, but also gives you medical benefits. Learn about the benefits, drawbacks, and some myths about mammograms. (Source: About.com Breast Cancer)
Date: 09 Jun 2013
If you're curious about your risk of being diagnosed with breast cancer, here are some online tools to help you. Most of these are simple questionnaires. None of these require you to enter confidential information, or to sign up for an account. I have tried all of these tools and reviewed them for you. (Source: About.com Breast Cancer)
Date: 09 Jun 2013
Medical menopause is different than natural and surgical menopause. It may occur during treatment for breast cancer. Learn more about the specifics and causes of medical menopause. (Source: About.com Breast Cancer)
Date: 09 Jun 2013
During chemotherapy for breast cancer, you may see changes in your finger and toenails, due to the drugs being used. Nails can change color, become fragile, and even come loose. Here are some ways to take care of your toenails, and prevent problems, while taking chemotherapy for breast cancer. (Source: About.com Breast Cancer)
MedWorm Sponsor Message: Have a look at The Breast Cancer Daily, the new breast cancer portal with all the latest breast cancer news and research powered by MedWorm, updated daily.
Date: 09 Jun 2013
Dr. William Gradishar, an oncologist at Feinberg School Medicine at Northwestern University in Chicago, answered ten commonly-asked questions about breast cancer. He addresses concerns about the possible causes of breast cancer, and gives information about treatment. Read what he has to say. (Source: About.com Breast Cancer)
Date: 09 Jun 2013
Flaxseed comes from the plant that is used to make linen, as well as flax meal and flaxseed oil. It has lignans and omega-3 fatty acids that are power anticancer components. Learn how flaxseed may benefit you. (Source: About.com Breast Cancer)
Date: 09 Jun 2013
Grief and loss are no strangers to those who deal with breast cancer. The loss of a breast or a loved one can trigger grieving, which is a natural response to loss. Understand more about coping with stages of grief and their effects. (Source: About.com Breast Cancer)
Date: 09 Jun 2013
Most of the benefits of motherhood are intangible, emotional, and social. But here's some evidence that pregnancy gives you a gift of health -- an edge against developing breast cancer. Read more to find out how pregnancy helps reduce your risk of developing breast cancer. (Source: About.com Breast Cancer)
Date: 09 Jun 2013
Lymphoscintigraphy is a technique that is used to determine the sentinel lymph node (first lymph nodes the tumor is draining into). (Source: About.com Breast Cancer)
MedWorm Sponsor Message: Have a look at The Breast Cancer Daily, the new breast cancer portal with all the latest breast cancer news and research powered by MedWorm, updated daily.
Date: 09 Jun 2013
If you found a breast lump and worry about atypical ductal hyperplasia (ADH) then you need to know the symptoms, diagnosis, and treatments for this condition. Atypical ductal hyperplasia does not always lead to breast cancer, but some women need to be vigilant. (Source: About.com Breast Cancer)
Date: 09 Jun 2013
Basophils are a type of white blood cell (leukocyte). These cells help you fight infections by releasing histamine and other chemicals that help to dilate your blood vessels when your immune response is triggered. (Source: About.com Breast Cancer)
Date: 09 Jun 2013
Many breast cancer patients need to take chemotherapy treatments to prevent a recurrence, or shrink a tumor, or help control the disease. Chemotherapy affects healthy tissue as well as cancer cells, and may cause side effects. Learn about the most standard chemo regimens for breast cancer, and how they may affect your cancer and your fertility. Understand the basics of chemotherapy for breast cancer. (Source: About.com Breast Cancer)
Date: 09 Jun 2013
There is life after breast cancer. Survivors change jobs, become activists, patient advocates, health bloggers, artists, and writers after breast cancer. Here are some examples of life after breast cancer. (Source: About.com Breast Cancer)
Date: 09 Jun 2013
A seroma can occur after surgery or breast brachytherapy. Seromas may be painful or cause mild discomfort. Learn more about seromas here. (Source: About.com Breast Cancer)
MedWorm Sponsor Message: Have a look at The Breast Cancer Daily, the new breast cancer portal with all the latest breast cancer news and research powered by MedWorm, updated daily.
Date: 09 Jun 2013
Adenosis, or enlarged breast lobules, can be so small you can't feel them, or so large they can't be distinguished from a cancerous lump. Adenosis will show up on a mammogram, but still may imitate breast cancer. Read more to learn about breast adenosis. (Source: About.com Breast Cancer)
Date: 09 Jun 2013
A definition and description of lobular carcinoma in situ, with signs and symptoms, and treatment. Learn more about lobular carcinoma in situ (LCIS) here. (Source: About.com Breast Cancer)
Date: 09 Jun 2013
(Society of Nuclear Medicine) For patients with advanced breast cancer, positron emission tomography and magnetic resonance imaging can improve quality of life and survival by providing physicians with information on the effectiveness of chemotherapy prior to surgery, say researchers presenting at the 2013 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging. (Source: EurekAlert! - Medicine and Health)
Date: 09 Jun 2013
Reducing radiation dosage would also help, study found (Source: Cancercompass News: Breast Cancer)
Date: 09 Jun 2013
Despite some recommendations to the contrary, women in their 40s have continued to receive annual mammograms. (Source: Breast Cancer Chronicles)
MedWorm Sponsor Message: Have a look at The Breast Cancer Daily, the new breast cancer portal with all the latest breast cancer news and research powered by MedWorm, updated daily.
Date: 09 Jun 2013
Enjoy outdoor cooking while keeping cancer risk to a minimum, expert urges (Source: Cancercompass News: Breast Cancer)
Date: 08 Jun 2013
There is nothing sexy about a woman with breast cancer having to have one or both of her breasts surgically removed as part of a humiliating mastectomy, or having to undergo toxic chemotherapy and radiation treatments that leave her bald and severely immuno-compromised... (Source: NaturalNews.com)
Date: 08 Jun 2013
Model shows if most moms breast-fed for a year, cancer and heart attacks could be reduced - and health care costs could be spared (Source: Health News: CBSNews.com)
Date: 07 Jun 2013
A single-center study analyzed the frequency of breast cancer susceptibility mutations among black women diagnosed with breast cancer. The findings suggest that broader genetic screening may be beneficial for these women. The study also suggests that family history is not the only criteria by which patients at risk for breast cancer can be identified. (Source: Cancer Network)
Date: 07 Jun 2013
In a study presented at ASCO, a team of researchers used microarrays to characterize 130 triple-negative breast cancer patients treated with neoadjuvant chemotherapy to see whether certain subtypes are more likely to respond to the treatment. (Source: Cancer Network)
MedWorm Sponsor Message: Have a look at The Breast Cancer Daily, the new breast cancer portal with all the latest breast cancer news and research powered by MedWorm, updated daily.
Date: 07 Jun 2013
Funded by volleyball tournaments, a new study released this week shows success in pinpointing individualized treatment for women with metastatic breast cancer, according to George Mason University researchers. The Side-Out Foundation's pilot study is part of a cutting-edge approach to personalized medicine that looks beyond genomic analysis alone to combine it with what some say is the next frontier in targeted therapy: proteomics... (Source: Health News from Medical News Today)
Date: 07 Jun 2013
Reaching puberty at an unusually early age can have adverse effects on social behavior and psychological development, as well as physical effects, including short stature, and lifelong health risks, such as diabetes, breast cancer and heart disease. Researchers at Brigham and Women's Hospital (BWH), in a multi-institutional collaboration with Boston Children's Hospital, the Broad Institute, and the University of Sao Paulo, Brazil, have identified that a genetic mutation leads to a type of premature puberty, known as central precocious puberty... (Source: Health News from Medical News Today)
Date: 07 Jun 2013
If new moms adhered to the recommended guidelines that urge them to breast-feed each child they give birth to for at least one year, they could theoretically stave off up to 5,000 cases of breast cancer, about 54,000 cases of hypertension and nearly 14,000 heart attacks annually. (Source: RWJF News Digest - Public Health)
Date: 06 Jun 2013
If new moms adhered to the recommended guidelines that urge them to breast-feed each child they give birth to for at least one year, they could theoretically stave off up to 5,000 cases of breast cancer, about 54,000 cases of hypertension and nearly 14,000 heart attacks annually. (Source: RWJF News Digest - Public Health)
Date: 06 Jun 2013
When you need sibling support most, don’t allow past grievances to make a difficult time even harder.read more (Source: Psychology Today Relationships Center)
MedWorm Sponsor Message: Have a look at The Breast Cancer Daily, the new breast cancer portal with all the latest breast cancer news and research powered by MedWorm, updated daily.
Date: 06 Jun 2013
Black women with breast cancer are more likely than the general population to have genetic mutations linked to their disease. Medscape Medical News (Source: Medscape Today Headlines)
Date: 06 Jun 2013
By Justine Cadet
Oftentimes children are cautioned against growing up too quickly; however, researchers may have uncovered a genetic cause for the small subset of boys and girls who physically undergo puberty at uncharacteristically young ages.
Precocious puberty, which is defined by the development of secondary sexual characteristics before 8 years in girls and 9 years in boys, has been associated with an increase in conduct and behavioral disorders during adolescence. The disorder affects more girls than boys, and is becoming more common, although the reasons for this are unclear.
Recently, the media has questioned whether puberty is starting earlier, even in those children without this condition. And a 2011 study by the American Academy of Pediatrics (AAP) followed American girls of var...
Date: 06 Jun 2013
Radiotherapy is a better option than surgical dissection for women with breast cancer and a positive sentinel lymph node, new research suggests. Medscape Medical News (Source: Medscape Today Headlines)
Date: 06 Jun 2013
A phase III trial presented at ASCO showed similar efficacy between two adjuvant paclitaxel regimens, but the weekly regimen led to fewer patient side effects. (Source: Cancer Network)
Date: 06 Jun 2013
A joint project between the Griffith University and the UQ Centre for clinical Research (UQCCR) has characterised an in vitro model that allows further studies on the breast cancer biology. These studies include the confirmation that primary tissue obtained from patients with breast cancer behaves similarly to those derived from long-term cultured cell lines. Griffith University's Associate Professor Alejandro Lopez said the team was working towards making breast cancer stem cells the target of specific cancer therapies, to improve current treatment outcomes... (Source: Health News from Medical News Today)
MedWorm Sponsor Message: Have a look at The Breast Cancer Daily, the new breast cancer portal with all the latest breast cancer news and research powered by MedWorm, updated daily.
Date: 06 Jun 2013
New research provides critical insights into how normal breast precursor cells may be genetically vulnerable to develop into cancer. The research is published in the inaugural issue of Stem Cell Reports, an open-access journal from the International Society of Stem Cell Research (ISSCR) published by Cell Press. Scientists discovered that a particular class of normal breast precursor cells have extremely short chromosome ends (known as telomeres). As a result, these cells would be expected to be prone to acquiring mutations that lead to cancer if they managed to stay alive... (Source: Health News from Medical News Today)
Date: 06 Jun 2013
(Centro Nacional de Investigaciones Oncologicas (CNIO)) A study published today by scientists from the Spanish National Cancer Research Centre describes how a genetic duplication that took place in the vertebrate ancestor some 500 million years ago encouraged the evolution of the ASF1b gene; a gene essential for proper cell division and related to some types of cancer such as breast cancer. The results of the study are published in Molecular Biology and Evolution, one of the most prestigious journals in the field of molecular biology and evolution. (Source: EurekAlert! - Medicine and Health)
Date: 05 Jun 2013
CHICAGO (MedPage Today) -- Older breast cancer patients received costly brachytherapy significantly more often at for-profit hospitals, despite a lack of clear evidence of benefit, a large retrospective review suggested. (Source: MedPage Today State Required CME)
Date: 05 Jun 2013
Disease stage and genetic factors may be related to women's treatment decisions, study shows (Source: Cancercompass News: Breast Cancer)
Date: 05 Jun 2013
Focus on colon, breast cancer drug06/05/2013 (Source: Kidney Cancer Association)
MedWorm Sponsor Message: Have a look at The Breast Cancer Daily, the new breast cancer portal with all the latest breast cancer news and research powered by MedWorm, updated daily.
Date: 05 Jun 2013
Breast cancer charity Susan G. Komen for the Cure said it was canceling fundraising walks next year in seven cities where money goals have not been met. Reuters Health Information (Source: Medscape Medical News Headlines)
Date: 05 Jun 2013
CHICAGO (MedPage Today) -- Breast cancer patients obtained the same disease control with less toxicity when they received weekly low-dose chemotherapy instead of a higher dose given every 2 weeks, results of a randomized trial showed. (Source: MedPage Today OB/GYN)
Date: 05 Jun 2013
A study presented at ASCO shows that axillary radiotherapy results in similar outcomes to axillary lymph node dissection, but halved the incidence of lymphedema. (Source: Cancer Network)
Date: 05 Jun 2013
The long-standing mystery behind dormant disseminated breast tumor cells and what activates them after years and even decades of latency may have been solved. Researchers with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) have identified the microenvironment surrounding microvasculature - the small blood vessels that transport blood within tissues - as a niche where dormant cancer cells reside. When these blood vessels begin to sprout, the new tips produce molecules that transform dormant cancer cells into metastatic tumors... (Source: Health News from Medical News Today)
Date: 05 Jun 2013
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